An Introduction to qPCR

Polymerase chain reaction (PCR) is construed aslaboratory technique based on the polymerase
one of the pioneering molecular biology techniqueschain reaction, which is used to amplify and
of the 90's. In fact, it was THE technique thatsimultaneously quantify a targeted DNA molecule
completely revolutionized molecular biology. Itsin a given sample. The qPCR applications include
been more than a decade of PCR domination ingene quantification, pathogen detection and
molecular biology and clinical diagnostic labs,validation of drug targets. Quantitation is not a
worldwide. The technique has evolved with thesenew idea in molecular biology. HIV viral loads in
passing years, and now, it is quantitative PCRAIDS patients have been analyzed since decades
(qPCR) which is getting the same attention and isnow. These days, the focus is on quantitation
becoming one of the most widely used molecularbecause of the advancements in genomic
biology techniques of this new millennium.research.
Quantitative PCR, as the name suggests, is a