Antibody Stabilization

ent">2. Chemical purification tools
Antibodies form the most fundamental unit of the3. Chemical sensors
human immune system. They are proteins that4. Explosive sensors
fight against foreign agents such as bacteria,5. Chemical synthesis pathway control and
viruses and fungi. Vaccines cause the productionmodulation
of antibodies against specific diseases in the body.6. Bioremediation devices
Antisera are prepared by inoculating animals with7. Antibody chip technology
certain antigens. When this is done, the animal8. Pre-vaccination against new diseases
produces antibodies against these antigens. TheNew applications in several other industries are
antibody secretion is collected as antisera.also possible. In addition to the development of
Antibodies and antiserum form the basis of theimmunotherapeutic and immunodiagnostic industry,
immunodiagnostics and immunotherapeuticstabilized antibodies can give rise to business
industry.opportunities in non-medical fields also. The
However, it has not been possible to developpotential of antibodies has not been used
antibodies very extensively because of theircompletely because of the stability issues
stability issues. Antibodies lose their function if notassociated with it. They are only moderately
handled carefully and gently. They are stable onlystable and lose their function if structural changes
in controlled environments with cold temperature.take place. Thus, protein stabilization is important.
Due to this it has not been possible to useScientists are researching ways of stabilizing the
antibodies for non-medical research. Sinceamino acids that make up the antibodies. They
antibodies are made of proteins, antibodyhave been able to achieve antibodies that are
stabilization basically involves aiming for protein100,000 times more stable than the normal
stability.antibodies. If better results are achieved it will
Stabilized antibodies can have potential applicationsbecome possible to use antibodies for other
in the field of:applications as well such as environmental
1. Forensic analysisremediation, biosensors and diagnostic reagents.