The evolution of validation – from paper to database

Ever since the introduction of the PDA model forcompliance business processes including
validation and its evolution into the GAMP VSarbanes-Oxley, FDA and EU regulations, Payment
model, validation has been plagued with theCard Industry (PCI), HIPAA and HITEC. With over
reputation of being a paper intensive and20 years experience across drug and device
burdensome process.regulated companies from Fortune 500 to
 Start-Ups, THINQ has also performed compliance
Regulatory agencies have come to expect abest practices training, FDA audits, Policy
certain type and style of document evidence todevelopment for electronic records and electronic
support the validation process including a validationsecurity (e.g. 21CFRPart11). With the new release
plan, requirements document and test protocolsof TCM, THINQ is also positioned to help Life
including the Installation, Operational andSciences companies move from burdensome cost
Performance qualifications.driven validation models to one that embodies a
 single, cost effect compliance system of record.
In recent years, these documents have been 
enhanced with risk management and mitigationTCM changes the paradigm for validation being a
approaches but the end result is even moreburdensome paper intensive exercise to a cost
paper. Additionally, the necessity to show derivedeffective process that provides a single system
relationships between content in documents usingof record for all compliance content. Many
a traceability matrix has added to the burden. Fortraditional paper based tasks are automated
many organizations in the Life Sciences industryincluding the generation of a complete traceability
the traceability matrix has created significantmatrix for all content and a fully automated
workload in an attempt to derive ongoing valuetesting process that generates test evidence and
for validating patches, fixes and process orstores it electronically. Full electronic signatures and
equipment changes prevalent throughout the lifeaudit trails are available within the compliance
cycle of any system.database. What’s more TCM is an industry
 proven solution that is available today especially
THINQ Compliance Inc formerly known as PENSAwhen compared to existing tools on the market
Technology Solutions Ltdprovides innovativeor when compared to the expense of building a
compliance and validation solutions tosolution from scratch.
pharmaceutical, blood products, medical device and 
other similar Life Sciences organizations. THINQ isThe end result is a secure compliance content
a thought leader in computer system validationrepository that provides best practice approaches
with a unique software application called THINQfor all types of system and equipment validation.
Compliance Manager or TCM that can beWith improved data management inherent in
combined with quality engineering consulting todatabases critical compliance information is
deliver risk based and cost effective complianceavailable across the organization to be reused,
solutions. THINQ's compliance experience extendsmeasured and reported with a great degree of
to many mission critical software applicationsefficiency.
including ERP, LIMS, DMS, MES, PLMS and to